derange mentally, throw out of mental balance; make insane
The death of his parents unbalanced him.
source: WordNet 3.0
throw into great confusion or disorder
Fundamental Islamicists threaten to perturb the social order in Algeria and Egypt.
source: WordNet 3.0
To put out of place, order, or rank; to disturb the proper arrangement or order of; to throw into disorder, confusion, or embarrassment; to disorder; to disarrange; as, to derange the plans of a commander, or the affairs of a nation.