a long-haired dog formerly trained to crouch on finding game but now to point
source: WordNet 3.0
One who, or that which, sets; -- used mostly in composition with a noun, as typesetter; or in combination with an adverb, as a setter on (or inciter), a setter up, a setter forth.
source: Webster 1913
verb
To cut the dewlap (of a cow or an ox), and to insert a seton, so as to cause an issue.